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Related post: Isolation and Serotypic Characterization of Human and Animal Rotaviruses PRINCIPAL INVESTIGATOR (List other professional personnel below the Principal Investigator ) (Name, title, laboratory and institute affiliation) PI: Yasutaka Hoshino, D.V.M. Visiting Scientist Others: Mitzi Sereno Albert Z. Kapikian, M.D. Microbiologist Head, Epid. Section LID, NIAID LID, NIAID LID, NIAID COOPERATING UNITS (if Minomycin Tablets 50mg any) Texas A & M University (Woode); University of Pavia, Italy (Gerna) LAB/BRANCH Laboratory of Infectious Diseases SECTION Epidemiology Section INSTITUTE AND LOCATION NIAID, NIH, Bethesda, MP 20892 TOTAL MAN- YEARS: 0.4 PROFESSIONAL: 0.2 0.2 CHECK APPROPRIATE BOX(ES) □ (a) Human subjects □ (a1) Minors □ (a2) Interviews (b) Human tissues D (c) Neither SUMMARY OF WORK (Use standard unreduced type. Do not exceed the Minomycin Tablets space provided.) Bovine rotavirus strain B223 was shown, by a two-way cross-neutralization assay, to be distinct from any of the 9 established serotypes. In addition, approximately 75% of the VP7 gene has been sequenced and available data are consistent with its designation as a new serotype. 11-55 PHS 6040 (Rav. 1/84) GPO S14-41* PROJECT NUMBER DEPARTMENT OF HEALTH AND HUMAN SERVICES - PUBLIC HEALTH SERVICE NOTICE OF INTRAMURAL RESEARCH PROJECT \ Z01 AI 00340-09 LID PERIOD COVERED October 1, 1989 to September 30, 1990 TITLE OF PROJECT (80 characters or less. Title must lit on one line between the borders.) Experimental Studies of Various Rotaviruses and Their Reassortants in Animals PRINCIPAL INVESTIGATOR (Ust other professional personnel below the Principal Investigator.) (Name, title, laboratory, and institute affiliation) PI: Yasutaka Hoshino, D.V.M. Visiting Scientist LID, NIAID Others: Mitzi M. Sereno Microbiologist LID, NIAID Albert Z. Kapikian, M.D. Head, Epid. Section LID, NIAID COOPERATING UNITS (if any) Ohio Agricultural and Development Center, Ohio State University, Wooster, OH (Saif) lab;6Ranch Laboratory of Infectious Diseases SECTION Epidemiology Section INSTITUTE AND LOCATION NIAID, NTH, Bethesda, MD 20892 TOTAL MAN-YEARS: 0.8 PROFESSIONAL: 0.2 0.6 CHECK APPROPRIATE BOX(ES) □ (a) Human subjects □ (b) Human tissues Lj3 (c) Neither □ (a1) Minors □ (a2) Interviews SUMMARY OF WORK (Use standard unreduced type. Do not exceed the space provided.) Continued efforts have been made to delineate the genetic mechanisms underlying virulence of rotavirus in the newborn gnotobiotic piglet model. In addition to the gene encoding rotavirus outer capsid protein VP4 or VP7, the tenth gene appears to play an independent role in determining the virulence of rotavirus in the porcine model. Elucidation of the constellation Buy Minomycin of genes required for rotavirus virulence may have important implications for the development of effective rotavirus vaccine strategies. I 11- 56 PHS 6040 (Rov 1/84) cpoiimii PROJECT NUMBER DEPARTMENT OF HEALTH AND HUMAN SERVICES - PUBLIC HEALTH SERVICE NOTICE OF INTRAMURAL RESEARCH PROJECT Z01 AI 00341-09 LID PERIOD COVERED October 1, 1989 to September 30, 1990 TITLE OF PROJECT (80 characters or less. Title must lit on one line between the borders.) Evaluation of Live Attenuated Rotavirus Vaccines PRINCIPAL INVESTIGATOR (List other professional personnel below the Pnncipal Investigator. ) (Name, title, laboratory, and institute affiliation) PI: Albert Z. Kapikian, M.D. Head, Epid. Section LID, NIAID Others: J. Flores, M.D. Visiting Scientist LID, NIAID K. Y. Minomycin 50mg Green, Ph.D. Senior Staff Fellow LID, NIAID M. Gorziglia, Ph.D. Visiting Scientist LID, NIAID Y. Hoshino, D.V.M. Visiting Scientist LID, NIAID R. M. Chanock, M.D. Chief LID, NIAID COOPERATING UNITS (if any) Instituto de Biomedicina, Caracas, Venezuela (Perez-Schael); University of Rochester (Dolin, Madore, Christy); Johns Hopkins University (Midthun, Clements, Halsey, Black); University of Tampere (Vesikari, Ruuska), Vanderbilt University (Wright) LAB/BRANCH Laboratory of Infectious Minomycin Antibiotic Diseases
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